DE, de, or dE may refer to:

Human names De (surname), a Bengali family name Dé (footballer, 1940–1992), Ademar José Ribeiro, Brazilian football left-back Dé (footballer, born 1998), Cledson Carvalho da Silva, Brazilian football forward de, a nobiliary particle

Language and linguistics De (Cyrillic) (), a letter in the Cyrillic script German language (ISO 639-1 alpha-2 code) De (kana) (), a Japanese hiragana/katakana de (interjection), Albanian interjection de-, an English prefix denoting reversal, undoing, removing; intensifying; or from, off Downward entailing, in linguistic semantics, a property of a modifier that reduces the number or degree an expression

Media and business Condor (airline) (IATA code), a German airline Daily Express, a British tabloid newspaper Digital Extremes, a Canadian-operated computer and video game development studio Douwe Egberts, a coffee brand John Deere (NYSE stock ticker symbol), an American machinery manufacturer

Military Defence Estates, an agency of the UK Ministry of Defence Desert Eagle, a large-caliber semi-automatic pistol manufactured by Magnum Research Destroyer escort (US Navy hull classification symbol)

Places Dé, Mali, a commune and town in Mali De River, Mizoram, India Delaware, US state, abbreviated "DE" by the US Postal Service and others DE postcode area, for Derby and surrounding areas of England Germany (ISO 3166-1 alpha-2 country code) .de, the ccTLD for Germany Maluku (province), Indonesia (vehicle registration prefix DE)

Science, technology, and mathematics Design engineer, engineer whose specialty is design Desktop environment, a graphical user interface commonly based on a desktop metaphor Dextrose equivalent, the relative sweetness of sugars Diatomaceous earth, a naturally occurring, soft, siliceous sedimentary rock mineral Differential equation, an equation which derivatives of a function appear as variables Differential evolution, a method of mathematical optimization Doctor of Engineering, a degree equivalent to a Ph.D. in engineering Dwarf elliptical galaxy (dE), in astronomy Dynamics Explorer, a NASA satellite mission Haplogroup DE (Y-DNA), a human Y-chromosome DNA haplogroup in genetics ΔE (color space) (dE), a mathematical measurement of the distance between two points in a Lab color space

Other uses De (Chinese philosophy), a concept of integrity in Daoism and virtue in Confucianism Defensive end, a position in American and Canadian football Distance education, studying through a correspondence course De, a scale degree in tonic sol-fa (sharpened form of doh)

See also Department of Education, a common government department