Grizzle is a surname. Notable people with the name include:
David Grizzle, American business executive Mary Grizzle (1921–2006), American politician and advocate of the Equal Rights Amendment Stanley G. Grizzle (1918–2016), Canadian citizenship judge and labour union activist Trevor Lloyd Grizzle (born 1947), American academic and New Testament scholar
See also Grizzly Grizabella Dog coat