Akkineni is a Telugu surname that may refer to:
Akkineni Lakshmi Vara Prasada Rao, popularly known as L. V. Prasad, Indian film actor, producer and director Akkineni Ramesh Prasad son of Akkineni Lakshmi Vara Prasada Rao Akkineni Sreekar Prasad, film editor, grandson of L. V. Prasad Akkineni Kutumba Rao filmmaker Akkineni Nageswara Rao, Telugu film actor and producer Akkineni Nagarjuna, Telugu film actor and producer; son of Akkineni Nageswara Rao Amala Akkineni, actress; wife of Akkineni Nagarjuna Akkineni Naga Chaitanya, a Telugu film actor; son of Akkineni Nagarjuna Samantha Akkineni, actress; former wife of Akkineni Naga Chaitanya Akkineni Akhil, son of Akkineni Nagarjuna and Akkineni Amala
See also Daggubati-Akkineni family