HFE may refer to: Science and technology HFE (gene), a gene that encodes the Human hemochromatosis protein Hello from Earth, an interstellar radio message Hidden Field Equations, a cryptosystem H-parameter model (hFE), the current gain of a bipolar junction transistor Human factors engineering Hydrofluoroether, a solvent
Transport Hefei Luogang International Airport, in Anhui, China, now defunct Hefei Xinqiao International Airport, in Anhui, China Hertford East railway station, in England
Other uses Health First Europe Herschend Family Entertainment Corporation, an American entertainment company Horizontal Fiscal Equalisation, in Australia