Francis II may refer to:
Francis II, Duke of Brittany (1433–1488) Francesco II Gonzaga, Marquess of Mantua (1466–1519), ruler of the Italian city of Mantua Francis II of France (1544–1560), king of France Francis II, Duke of Lorraine (1572–1632), son of Charles III, Duke of Lorraine, and Claude of Valois Francesco II d'Este, Duke of Modena (1660–1694) Francis II Rákóczi (1676–1735), Prince of Transylvania Francis II, Holy Roman Emperor (1768–1835), last Holy Roman Emperor and first Austrian emperor Francis II of the Two Sicilies (1836–1894), last king of the Two Sicilies Franz, Duke of Bavaria (born 1933), called "Francis II" by supporters of the Jacobite claim to the thrones of England, Scotland, Ireland, and France Francis II, Duke of Saxe-Lauenburg (1547–1619), third son of Francis I of Saxe-Lauenburg and Sybille of Saxe-Freiberg
See also Francesco II (disambiguation) Franz Joseph II, Prince of Liechtenstein