Guagua is a municipality in Pampanga, Philippines.

Guagua may also refer to: Guagua (instrument), or catá, a Cuban percussion instrument Guagua de pan, a hispanicised word for the food T'anta wawa Guagua language, or Piaroa, an indigenous language of Colombia and Venezuela

People with the surname Jorge Guagua (born 1981), an Ecuadorian footballer