Rusche is a surname of German origin, being a variant of the surname Rusch. Notable people with the surname include:
Dietrich Rusche (1936-2024), German politician (CDU) Georg Rusche (1900-1950), German political economist and criminologist Herbert Rusche (1952-2024), German politician and LGBT activist John Rusche (born 1950), American politician Marjorie Rusche (born 1949), American composer
See also Carol Rusche Bentel (born 1957), American architect and educator Rusch Rushe