James Cox may refer to:
Politics James Cox (Nova Scotia politician) (died 1805), merchant and politician in Nova Scotia James Cox (New Jersey politician) (1753–1810), United States Representative from New Jersey, 1809–1810 James M. Cox (1870–1957), American politician, Governor of Ohio and Democratic presidential nominee in 1920 James P. Cox (1804–1866), member of the first legislature of the Wisconsin Territory
Media James Cox (director) (born 1975), American film director James Cox (journalist) (1941–2024), British radio and television presenter and correspondent for the BBC
Sports James Cox (quarterback) (born 1983), starting quarterback for the Colorado Buffaloes football team, 2005–2006 James Cox (baseball), Negro league baseball player James Allen Cox (born 1977), American professional wrestler better known as James Storm J. B. Cox (James Brent Cox, born 1984), American baseball player Jamie Cox (born 1969), cricketer Jamie Cox (boxer) (born 1986), professional boxer from Swindon
Business James Cox (inventor) (1723–1800), British jeweller, goldsmith and entrepreneur James M. Cox Jr. (1903–1974), American businessman, chair of Cox Enterprises James H. Cox (1810–1877), American teacher, businessman, legislator, judge
Others James Cox (labourer) (1846–1925), New Zealand labourer, flax worker, swagger and agricultural worker James Charles Cox (1834–1912), Australian physician and naturalist James L. Cox (born 1942), American cardiothoracic surgeon James Renshaw Cox (1886–1951), American Roman Catholic priest and 1932 candidate for President of the United States James Cox (priest) (1654–1716), Irish Anglican priest
See also Jim Cox (disambiguation) James Cocke, mayor of Williamsburg, Virginia James Cox Aikins (1823–1904), Canadian politician