Paul Nguyen may refer to:
Paul Nguyen (filmmaker), Canadian filmmaker, politician, and activist Paul L. Nguyen, American radiation oncologist and researcher Paul Lê Nguyễn, Vietnamese swimmer Paul Nguyễn Công Anh, Righteous Among the Nations Vietnamese national Paul Nguyễn Thanh Hoan, Vietnamese Roman Catholic bishop who served the Roman Catholic Diocese of Phan Thiết Paul Nguyễn Văn Hòa, Vietnamese Roman Catholic bishop who served the Roman Catholic Diocese of Nha Trang Paul Nguyễn Văn Bình, first Archbishop of Saigon